See what we’re doing
Animal Life Sciences has licensed multiple drug technologies developed at the MD Anderson Cancer Center for the following diseases in animals:
1
Advanced chemotherapies for the treatment of leukemias and brain tumors
2
Cell signaling modulators and inhibitors of glycolysis for the treatment of a wide range of tumors
3
Topical treatments for a wide range of cancerous and noncancerous inflammatory skin conditions
OUR DRUG PIPELINE
Current Stages of Development and Testing
DRUG PORTFOLIO
10 Drugs in Development Across 5 Different Indications
Alongside direct investment of $60 million, over $43 million of grant funding (total of $103 million USD) has gone towards the development of our robust drug development pipeline.
brain cancer
WPD101
- Indications to treat brain cancers including glioblastoma.
- Primary focus on GBM and subsequently on other cancers with similarly high overexpression of IL-13RA2 and EphA2 receptors (for example uveal melanoma).
Pancreatic Cancer
WP1234
- Indications to treat brain cancers including glioblastoma.
- WP1234 is a prodrug of 2-DG that increases half-life, has longer circulation time, but also enables release of an HDAC inhibiting short fatty acid, namely ethyl-butyric acid and higher uptake by the specific organs.
brain cancer
Berubicin
- Indications to treat Glioblastoma.
- Berubicin is an exciting new drug that is one of the first anthracyclines proven to cross the blood brain barrier (BBB) and able to reach brain tumors.
melanoma
WPD102
- Indications to treat Uveal Melanoma.
- Primary focus on primary UV and subsequently on liver UV lesions and related cancers with high overexpression of IL-13RA2.
melanoma
WP1220
- Indications to treat cutaneaous t-cell.
- WP1220 in Poland for the topical treatment of early stage CTCL patients. CTCL is a potentially deadly form of skin cancer for which there are limited treatment options.
Leukemia
Annamycin
- Indications to treat acute myeloid leukemia
- Annamycin has shown the potential to significantly improve health in a Phase I/II acute myeloid leukemia (AML) trial.
Multiple Tumors
WP1122
- Indications to treat pancreatic cancer & glioblastoma.
- WP1122 is a prodrug of 2-DG that increases half-life, enables higher uptake by the brain and overall improves drug-like properties.
Multiple Tumors
WP1066
- Indications to treat glioblastoma and melanoma brain metastases.
- WP1066 represents a new class of drugs, which ALS calls “Immune/Transcription Modulators.” WP1066 and related analogs have demonstrated the ability to directly induce apoptosis (tumor cell death).
Multiple Tumors
WPD103
- Indications to treat GBM, Melanoma & other cancers.
- WPD103 is a radiopharmaceutical based on the expression of tumor specific receptors, such as IL-13RA2 and EphA2, which are not detected in normal cells.
Pancreatic Cancer
WP1732
- Indications to treat pancreatic cancer.
- WP1732 is a potential breakthrough discovery, a new fully water-soluble p-STAT3 inhibitor technology complementary to orally bioavailable non-water-soluble WP1066.